Veratric acid

CAS No. 93-07-2

Veratric acid( 3,4-Dimethoxybenzoic acid )

Catalog No. M17718 CAS No. 93-07-2

Veratric acid plays an important role in producing antibiotics and various dyes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Veratric acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Veratric acid plays an important role in producing antibiotics and various dyes.
  • Description
    Veratric acid plays an important role in producing antibiotics and various dyes. They are used as intermediates for pharmaceuticals (especially for antipyretic analgesic, anti-rheumatism) and other organic syntheses. It is used as a matrix for ionization of peptides, proteins, and carbohydrates.(In Vitro):Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.(In Vivo):Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
  • In Vitro
    Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
  • In Vivo
    Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
  • Synonyms
    3,4-Dimethoxybenzoic acid
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    93-07-2
  • Formula Weight
    182.17
  • Molecular Formula
    C9H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (548.94 mM)
  • SMILES
    COc1c(cc(cc1)C(=O)O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee KE, et al. Arch Dermatol Res. 2016 Apr;308(3):183-92.
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